A full list of publications can be found on Pubmed.

Select publications from my research and collaborations include:

Clinical Informatics and Data Science:

Fohner AE, Greene JD, Lawson BL, Chen JH, Kipnis P, Escobar GJ, Liu VX. Assessing clinical heterogeneity in sepsis through treatment patterns and machine learning. J Am Med Inform Assoc. 2019 Jul 17;. doi: 10.1093/jamia/ocz106. [Epub ahead of print] PubMed PMID: 31314892.

Gottdiener JS, Fohner AE. Risk Prediction in Heart Failure: New Methods, Old Problems. JACC Heart Fail2020 Jan;8(1):22-24doi: 10.1016/j.jchf.2019.08.015. Epub 2019 Oct 9. PubMed PMID: 31606359.

Sridhar AR, Chen Amber ZH, Mayfield JJ, Fohner AE, Arvanitis P, Atkinson S, Braunschweig F, Chatterjee NA, Zamponi AF, Johnson G, Joshi SA, Lassen MCH, Poole JE, Rumer C, Skaarup KG, Biering-Sørensen T, Blomstrom-Lundqvist C, Linde CM, Maleckar MM, Boyle PM. Identifying risk of adverse outcomes in COVID-19 patients via artificial intelligence-powered analysis of 12-lead intake electrocardiogram. Cardiovasc Digit Health J2022 Apr;3(2):62-74doi: 10.1016/j.cvdhj.2021.12.003. Epub 2021 Dec 31. PubMed PMID: 35005676; PubMed Central PMCID: PMC8719367.

Pharmacogenetics/Precision Medicine:

Fohner AE, Ranatunga DK, Thai KK, Lawson BL, Risch N, Oni-Orisan A, Jelalian AT, Rettie AE, Liu VX, Schaefer CA. Assessing the clinical impact of CYP2C9 pharmacogenetic variation on phenytoin prescribing practice and patient response in an integrated health system. Pharmacogenet Genomics. 2019 Oct;29(8):192-199. doi: 10.1097/FPC.0000000000000383. PubMed PMID: 31461080.

Fohner AE, Robinson R, Yracheta J, Dillard DA, Schilling B, Khan B, Hopkins S, Boyer BB, Black J, Wiener H, Tiwari HK, Gordon A, Nickerson D, Tsai JM, Farin FM, Thornton TA, Rettie AE, Tummel KE. “Variation in genes controlling warfarin disposition and response in American Indian and Alaska Native people: CYP2C9, VKORC1, CYP4F2, CYP4F11, GGCX.” Pharmacogenet Genomics. 2015 Jul;25(7):343-53. PMID: 25946405

Fohner A, Muzquiz LI, Austin MA, Gaedigk A, Gordon A, Thornton T, Rieder MJ, Pershouse MA, Putnam EA, Howlett K, Beatty P, Thummel KE, Woodahl EL. “Pharmacogenetics in American Indian populations: analysis of CYP2D6, CYP3A4, CYP3A5, and CYP2C9 in the Confederated Salish and Kootenai Tribes.” Pharmacogenet Genomics. 2013 Aug;23(8):403-14. PMID: 23778323
Fohner AE, Brackman DJ, Giacomini KM, Altman RB, Klein TE. PharmGKB summary: very important pharmacogene information for ABCG2. Pharmacogenet Genomics. 2017 Nov;27(11):420-427. doi: 10.1097/FPC.0000000000000305. Review. PubMed PMID: 28858993; PubMed Central PMCID: PMC5788016.
Fohner AE, Sparreboom A, Altman RB, Klein TE. PharmGKB summary: Macrolide antibiotic pathway, pharmacokinetics/pharmacodynamics. Pharmacogenet Genomics. 2017 Apr;27(4):164-167. doi: 10.1097/FPC.0000000000000270. PubMed PMID: 28146011; PubMed Central PMCID: PMC5346035.
Fohner AE, Rettie AE, Thai KK, Ranatunga DK, Lawson BL, Liu VX, Schaefer CA. Associations of CYP2C9 and CYP2C19 Pharmacogenetic Variation with Phenytoin-Induced Cutaneous Adverse Drug Reactions. Clin Transl Sci2020 Sep;13(5):1004-1009doi: 10.1111/cts.12787. Epub 2020 Apr 18. PubMed PMID: 32216088; PubMed Central PMCID: PMC7485959.
Martinez MF, Alveal E, Soto TG, Bustamante EI, Ávila F, Bangdiwala SI, Flores I, Monterrosa C, Morales R, Varela NM, Fohner AE, Quiñones LA. Pharmacogenetics-Based Preliminary Algorithm to Predict the Incidence of Infection in Patients Receiving Cytotoxic Chemotherapy for Hematological Malignancies: A Discovery Cohort. Front Pharmacol2021;12:602676doi: 10.3389/fphar.2021.602676. eCollection 2021. PubMed PMID: 33776761; PubMed Central PMCID: PMC7988592.
Fohner AE, Dalton R, Skagen K, Jackson K, Claw KG, Hopkins SE, Robinson R, Khan BA, Prasad B, Schuetz EG, Nickerson DA, Thornton TA, Dillard DA, Boyer BB, Thummel KE, Woodahl EL. Characterization of CYP3A pharmacogenetic variation in American Indian and Alaska Native communities, targeting CYP3A4*1G allele function. Clin Transl Sci2021 Jul;14(4):1292-1302doi: 10.1111/cts.12970. Epub 2021 Jan 27. PubMed PMID: 33503331; PubMed Central PMCID: PMC8301563.

Public Health Policy/Practice Guidelines:

Fohner, A.E.  N.A Garrison, M.A Austin, W Burke. “Carnitine Palmitoyltransferase 1A P479L and Infant Death: Policy Implications of Emerging Data.” Genetics in Medicine. In press.

Fohner AE, Wang Z, Yracheta J, O’Brien D, Hopkins SE, Black J, Philip J, Wiener HW, Tiwari HK, Stapleton PL, Tsai JM, Thornton TA, Boyer BB, Thummel KE. “Genetics, Diet, and Season Are Associated with Serum 25-Hydroxycholecalciferol Concentration in a Yup’ik Study Population from Southwestern Alaska.” J. Nutr. dos: 10.3945/jn115.223388.

Karnes JH, Rettie AE, Somogyi AA, Huddart R, Fohner AE, Formea CM, Ta Michael Lee M, Llerena A, Whirl-Carrillo M, Klein TE, Phillips EJ, Mintzer S, Gaedigk A, Caudle KE, Callaghan JT. Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2C9 and HLA-B Genotypes and Phenytoin Dosing: 2020 Update. Clin Pharmacol Ther2021 Feb;109(2):302-309doi: 10.1002/cpt.2008. Epub 2020 Sep 6. Review. PubMed PMID: 32779747; PubMed Central PMCID: PMC7831382.

Research equity:

Fohner AE, Volk KG, Woodahl EL. Democratizing Precision Medicine Through Community Engagement. Clin Pharmacol Ther. 2019 Sep;106(3):488-490. doi: 10.1002/cpt.1508. Epub 2019 Jun 17. PubMed PMID: 31206610; PubMed Central PMCID: PMC6692197.


Dementia, Alzheimer’s Disease, Cognitive Decline:

Fohner AE, Bartz TM, Tracy RP, Adams HHH, Bis JC, Djousse L, Satizabal CL, Lopez OL, Seshadri S, Mukamal KJ, Kuller LH, Psaty BM, Longstreth WT Jr. Association of Serum Neurofilament Light Chain Concentration and MRI Findings in Older Adults: The Cardiovascular Health Study. Neurology. 2022 Mar 1;98(9):e903-e911. doi: 10.1212/WNL.0000000000013229. Epub 2021 Dec 17. PubMed PMID: 34921102; PubMed Central PMCID: PMC8901174.

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